Marina P. Dyakovich

Federal State Budgetary Scientific Institution «East-Siberian Institute of Medical and Ecological Research», Federal State Budget Educational Institution of Higher Education "Angarsk State Technical University"

An approach to the development of a controlled model of the dynamics of health status and health-related quality of life of patients with chronic mercury intoxication using traditional drug treatment, supplemented by neurorehabilitation technology (BOS-training) is proposed. The optimal control problem is set and numerically solved in order to improve the health and quality of life of such patients. The results of numerical experiments, scenarios of changes and optimal modes for different initial States are presented. The results obtained allow us to estimate the costs of drug treatment and rehabilitation of biofeedback training depending on the exposure of mercury load, causing the severity of the disease, as well as to identify the dynamics of the health of patients with a possible change in the control effects, taking into account the limited financial resources. The vector of further research is substantiated.

dynamic controlled model, occupational pathology, chronic mercury intoxication, exposure mercury load, numerical experiments